Key result
Female gender was associated with a 19% lower risk of incident prehypertension compared to men (HR 0.81), with incidence rates of 489 and 764 per 10,000 person-years, respectively.
Cohort (n=3,597)
No
In a Middle Eastern cohort, the incidence of prehypertension was high, with general adiposity and glomerular hyperfiltration predicting risk in both sexes, while 2-hour post-challenge plasma glucose was a specific risk factor for men and central adiposity for women.
Prehypertension is associated with cardiovascular disease (CVD). There is no study to examine the incidence and risk factors of prehypertension in a sex stratified setting. The aim of this study was to examine the effect modification of sex for different risk factors which predicts the progression from normotension to prehypertension in a Middle East populationbased cohort, during a median follow-up of 9.2 years.
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Hadaegh et al. (2015) conducted a cohort in Normotension (n=3,597). Female gender vs. Male gender was evaluated on Incident prehypertension (HR 0.81, 95% CI 0.69-0.94, p=0.01). Female gender was associated with a 19% lower risk of incident prehypertension compared to men (HR 0.81), with incidence rates of 489 and 764 per 10,000 person-years, respectively.
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