Key result
Patients with bicuspid aortic valve and preserved ejection fraction had a lower peak diastolic circumferential strain rate compared to controls (0.89 vs 1.21 s−1, P=.003).
Why the study?
Does feature-tracking cardiovascular magnetic resonance (CMR-FT) identify abnormalities in myocardial strain in patients with isolated bicuspid aortic valve and preserved ejection fraction compared to controls?
Population
Patients with isolated bicuspid aortic valve and preserved ejection fraction and controls.
Comparison
Feature-tracking cardiovascular magnetic… vs Controls (n=19)
Design
Case-control
Authors
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May signal early diastolic dysfunction in BAV; hypothesis-generating for CMR-FT in risk stratification.
Observational (n=61)
Does feature-tracking cardiovascular magnetic resonance (CMR-FT) identify abnormalities in myocardial strain in patients with isolated bicuspid aortic valve and preserved ejection fraction compared to controls?
Absolute Event Rate: 0.89% vs 1.21%
p-value: p=.003
Feature-tracking CMR identifies early subclinical diastolic dysfunction, evidenced by decreased circumferential diastolic strain rate, in asymptomatic patients with bicuspid aortic valve and preserved ejection fraction.
Burris et al. (2018) conducted an observational in Bicuspid Aortic Valve with preserved ejection fraction (n=61). Bicuspid aortic valve vs. Controls was evaluated on Peak diastolic circumferential strain rate (p=.003). Patients with bicuspid aortic valve and preserved ejection fraction had a lower peak diastolic circumferential strain rate compared to controls (0.89 vs 1.21 s−1, P=.003).
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