What question did this study set out to answer?

This study aims to evaluate the prognostic value of the combination of PLR and FIB for predicting overall survival in NSCLC patients treated with surgery.

December 1, 2023Journal of Thoracic DiseaseOpen Access

Combination of the platelet-to-lymphocyte ratio and fibrinogen may predict 5-year overall survival of patient in non-small cell lung cancer treated with surgery

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Authors

YLYiping LuoUniversity of Electronic Science and Technology of China KLKangni LinFujian Medical University MZMingji ZhangFujian Medical University

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Implication

Retrospective study finds that PLR-FIB predicts 5-year overall survival in NSCLC patients after surgery, implying potential for clinical use.

Key Points

This study aims to evaluate the prognostic value of the combination of PLR and FIB for predicting overall survival in NSCLC patients treated with surgery.
Conducted a retrospective analysis of 314 NSCLC patients who underwent surgery.
Divided patients into low-PLR-FIB and high-PLR-FIB groups based on a cutoff value.
Used univariate and multivariate analyses to assess the relationship between PLR-FIB and survival.
High PLR-FIB was significantly associated with poor outcomes (P=0.023).
Low PLR-FIB was an independent factor associated with better prognosis (HR, 0.587; 95% CI: 0.359-0.985; P=0.044).
5-year overall survival rates were 80.8% for the low-PLR-FIB group and 67.9% for the high-PLR-FIB group (P=0.02).

Cite This Study

Luo et al. (2023) studied this question.

synapsesocial.com/papers/6a1f552eda07783dec23508a https://doi.org/10.21037/jtd-23-1730

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Implication

Retrospective study finds that PLR-FIB predicts 5-year overall survival in NSCLC patients after surgery, implying potential for clinical use.

Combination of the platelet-to-lymphocyte ratio and fibrinogen may predict 5-year overall survival of patient in non-small cell lung cancer treated with surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

Combination of the platelet-to-lymphocyte ratio and fibrinogen may predict 5-year overall survival of patient in non-small cell lung cancer treated with surgery

Discussion

Member takes

Implication

Key Points

Cite This Study

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