April 6, 2013BloodOpen Access

The laboratory and the direct oral anticoagulants

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Design

Review

Authors

ATArmando TripodiCross-Cutting Cardiology

Discussion

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Implication

Supports targeted assay selection for dabigatran or rivaroxaban when measurement is required; leaves open need for outcome-validated prospective studies.

Structured PICO

Intervention

Laboratory measurement of direct oral anticoagulant effect

Although direct oral anticoagulants do not routinely require monitoring, specific assays (dilute-thrombin/ecarin for dabigatran, PT/anti-FXa for rivaroxaban) are recommended when clinical situations demand measurement of their anticoagulant effect.

Cite This Study

Armando Tripodi (2013) studied this question.

synapsesocial.com/papers/6a1f56efe800721f04835546 https://doi.org/10.1182/blood-2012-12-453076

Topics

Anticoagulation in AF

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Implication

Supports targeted assay selection for dabigatran or rivaroxaban when measurement is required; leaves open need for outcome-validated prospective studies.

The laboratory and the direct oral anticoagulants

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Topics

The laboratory and the direct oral anticoagulants

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Topics

Also Consider