Answers are grounded in this paper and cite their sources.
Experimental modeling demonstrates CD38's regulation of cGAMP activity in multiple myeloma, indicating its role in disease progression.
molecular modeling and cell-free biochemical assays to show a direct interaction between the catalytic pocket of CD38 and cGAMP. Altogether, our findings expand the current knowledge about the regulation of cGAMP activity.
No takes yet. Share an insight, caveat, or question.
Cuollo et al. (2024) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: