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Polycaprolactone (PCL) and its derivatives are highly versatile, biodegradable, and biocompatible biomaterials that offer significant advantages for diverse healthcare applications, including drug delivery, tissue engineering, and implantable devices. Novelty: ClaimNovelty.SYNTHESIS. Consensus alignment: ConsensusAlignment.NEUTRAL.

July 14, 2023Polymers for Advanced Technologies93 citationsOpen Access

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Polycaprolactone and its derivatives for drug delivery

RPRanjitsinh PawarBharati Vidyapeeth Deemed University APAnam PathanDr. D. Y. Patil Medical College, Hospital and Research Centre SNSrishti NagarajUniversity of Copenhagen

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Abstract

Abstract Polycaprolactone (PCL) is polymer of 21st centuries. PCL is a biodegradable and biocompatible polymer used for various healthcare applications. This review explores the properties, synthesis, and processing of PCL. The use of PCL polymer for nanoparticles (NPs), microparticles, films, and fibers offers several advantages for biomedical applications. The review highlights the potential of PCL‐based materials for tissue engineering, drug delivery, wound healing, and implantable medical devices. We also critically analyzed challenges in PCL‐based materials and the strategies used to overcome for successful translation into clinical applications. Overall, this review provides a comprehensive overview of PCL as a valuable biomaterial for healthcare applications.

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Polycaprolactone and its derivatives for drug delivery

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