An age-dependent compartment model is applied in a novel way to survival data. Analysis is performed of data from an “improved survival experiment” which incorporates serial sacrifice, and tests of hypotheses of dependent diseases are obtained. Problems dealing with identifiability of models are emphasized and discussed. Finally, these ideas are illustrated in connection with experimental data from mice exposed to radiation.
No takes yet. Share an insight, caveat, or question.
Berlin et al. (1979) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: