Why the study?
Does manipulation of loading conditions affect regional segmental motion in acutely ischemic myocardium in conscious dogs?
Does manipulation of loading conditions affect regional segmental motion in acutely ischemic myocardium in conscious dogs?
In acutely ischemic myocardium, systolic bulging is load-dependent and relies on preload tension, while shortening during isovolumic relaxation is a completely passive phenomenon.
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Preload reduction augments ischemic segment motion in dogs; leaves open translation to human acute ischemia assessment.
Akaishi et al. (1986) studied this question.
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