Key result
Unplanned ICU readmission linked to ~10-fold higher in-hospital mortality versus non-readmitted patients.
Why the study?
ICU readmissions remain a critical concern, carrying increased morbidity, mortality, and cost.
Population
185,241 adult ICU admissions across 19 hospitals and the MIMIC-IV database
Comparison
ICU readmissions vs initial ICU stays or no readmission
Design
Multicenter cohort study
Follow-up
Same hospitalization
Authors
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Unplanned ICU readmissions mark high-mortality patients warranting closer surveillance; extends large observational data but leaves preventive interventions for prospective trials.
Cohort (n=185,241)
Yes
Unplanned ICU readmissions occur in 8.6% of discharges and are associated with a nearly 10-fold increase in in-hospital mortality and greater need for organ support.
Amagai et al. (2025) conducted a cohort in ICU survivors transferred to a non-ICU floor (n=185,241). ICU discharge to a non-ICU floor was evaluated on Unplanned ICU readmission during the same hospitalization. Unplanned ICU readmissions occurred in 8.6% of adult ICU discharges and were associated with a significantly higher in-hospital mortality rate (20.6%) compared to non-readmitted patients (2.1%).
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