Key result
Among women with non-obstructive coronary artery disease not on statins, triglycerides independently predicted major adverse cardiovascular events (HR 1.25 per 50 mg/dL; 95% CI 1.06-1.47; P=0.01).
Why the study?
Women with non-obstructive coronary artery disease have increased cardiovascular morbidity, but the role of risk factors in this population is not yet established.
Do triglyceride levels and triglyceride/HDL ratio predict major adverse cardiovascular events in patients with non-obstructive coronary artery disease?
Cohort (n=462)
Do triglyceride levels and triglyceride/HDL ratio predict major adverse cardiovascular events in patients with non-obstructive coronary artery disease?
Hazard Ratio: 1.25 (95% CI 1.06–1.47)
p-value: p=0.01
Elevated triglyceride levels independently predict major adverse cardiovascular events in women with non-obstructive coronary artery disease who are not on statin therapy.
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Triglycerides may identify higher-risk statin-naive women with non-obstructive CAD; hypothesis-generating and should not yet change practice.
Prasad et al. (2019) conducted a cohort in Non-obstructive coronary artery disease (n=462). Triglyceride levels vs. Lower triglyceride levels was evaluated on Major adverse cardiovascular events (MACE) (HR 1.25, 95% CI 1.06-1.47, p=0.01). Among women with non-obstructive coronary artery disease not on statins, triglycerides independently predicted major adverse cardiovascular events (HR 1.25 per 50 mg/dL; 95% CI 1.06-1.47; P=0.01).
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