May 1, 1992Archives of Internal Medicine
Gender Differences in the Treatment and Outcome of Acute Myocardial Infarction
Why the study?
Are there gender differences in the treatment and in-hospital mortality of acute myocardial infarction?
Population
4891 consecutive patients hospitalized for acute myocardial infarction in 19 hospitals in the Seattle…
Comparison
Female gender vs Male gender
Design
Cohort
Follow-up
in-hospital
Authors
Discussion
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Implication
Disparities in AMI care for women should not yet change practice; leaves open whether age and selection explain mortality gaps.
Key Points
- This study aims to compare the treatment approaches and outcomes of acute myocardial infarction between women and men.
- Hospital records of 4891 patients (1659 women) were reviewed from January 1988 to June 1990.
- Data on treatments, complications, and mortality were analyzed using the Myocardial Infarction Triage and Intervention Registry.
- Treatment modalities examined included thrombolytic therapy, coronary angiography, angioplasty, and bypass surgery.
- Thrombolytic therapy was used less often in women; eligibility details were not fully assessed.
- Hospital mortality rates were 16% for women and 11% for men, with age adjustment diminishing this difference.
- Coronary angiography and angioplasty were underutilized in women, though rates of procedural outcomes were similar for both genders among those receiving angiography.
Structured PICO
Are there gender differences in the treatment and in-hospital mortality of acute myocardial infarction?
P
Population
4891 consecutive patients (1659 women) hospitalized for acute myocardial infarction in 19 hospitals in the Seattle (Wash) metropolitan area between January 1988 and June 1990.
I
Intervention
Female gender
C
Comparator
Male gender
O
Outcome
In-hospital treatments (thrombolytic therapy, coronary angiography, angioplasty, bypass surgery), in-hospital complications, and deathhard clinical
This study highlights significant gender disparities in the management of acute myocardial infarction, with women receiving fewer invasive procedures and thrombolytic therapies compared to men.
Limitations
- Information about eligibility for thrombolytic treatment was not available to determine if difference was due to treatment bias or differences in eligibility
Cite This Study
Charles Maynard (1992) studied this question.