What does this research mean for the field?

Asymptomatic ST segment depression in patients with coronary artery disease is accompanied by significant elevations in pulmonary artery diastolic pressure that are hemodynamically indistinguishable from painful ischemic episodes. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 1, 1986HeartOpen Access

The haemodynamic significance of asymptomatic ST segment depression assessed by ambulatory pulmonary artery pressure monitoring.

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Why the study?

Does asymptomatic ST segment depression have similar haemodynamic significance to painful ST segment depression in men with coronary artery disease?

Population

19 men with clinical and angiographic evidence of coronary artery disease, and 6 normal subjects.

Comparison

Ambulatory pulmonary artery pressure monitoring… vs Normal subjects during exertion / Painful ST…

Design

Cohort

Follow-up

24-48 hours

Authors

RLRichard LévyTélécom Paris LSLeonard M. ShapiroStructural Heart Disease CWChristine WrightBrain Tumour Charity

Discussion

Member takes

Implication

Asymptomatic ST depression associates with comparable hemodynamic derangements; leaves open whether it warrants equivalent intervention in CAD.

Structured PICO

Does asymptomatic ST segment depression have similar haemodynamic significance to painful ST segment depression in men with coronary artery disease?

Population

19 men (mean age 57.7) with clinical and angiographic evidence of coronary artery disease, and 6 normal subjects.

Intervention

Ambulatory pulmonary artery pressure monitoring using a transducer-tipped catheter with simultaneous frequency modulated electrocardiograms for 24-48 hours

Comparator

Normal subjects during exertion (for PA pressure comparison) / Painful ST segment depression episodes (internal comparison)

Outcome

Change in pulmonary artery diastolic pressure during episodes of ST segment depressionsurrogate

Painless ST segment depression in patients with coronary artery disease is accompanied by similar haemodynamic derangements (elevated pulmonary artery diastolic pressure) as painful ischemic episodes.

Cite This Study

Lévy et al. (1986) studied this question.

synapsesocial.com/papers/6a1fac47e47f012c48075795 https://doi.org/10.1136/hrt.56.6.526

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Implication

Asymptomatic ST depression associates with comparable hemodynamic derangements; leaves open whether it warrants equivalent intervention in CAD.

The haemodynamic significance of asymptomatic ST segment depression assessed by ambulatory pulmonary artery pressure monitoring.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

The haemodynamic significance of asymptomatic ST segment depression assessed by ambulatory pulmonary artery pressure monitoring.

Discussion

Member takes

Implication

Structured PICO

Cite This Study

Also Consider

Also Consider