Colloidal gold immunochromatographic assay for mycophenolic acid in human plasma

Jiayi Liu; Lingling Guo; Liqiang Liu; Xinxin Xu; Hua Kuang; Chuanlai Xu

doi:10.1039/d6an00484a

January 1, 2026The Analyst

Colloidal gold immunochromatographic assay for mycophenolic acid in human plasma

View at Publisher

Ask AI

Bookmark

Share

Key Points

This research aims to develop a reliable assay for monitoring mycophenolic acid levels in human plasma to prevent toxicity and transplant rejection.
Developed a colloidal gold immunochromatographic assay for mycophenolic acid.
Utilized human plasma samples to validate the assay's effectiveness.
Analyzed assay sensitivity and specificity in detecting MPA levels.
The assay demonstrated high sensitivity, detecting MPA concentrations accurately within the therapeutic range.
Specificity was confirmed, minimizing cross-reactivity with other substances in human plasma.
Improved monitoring of MPA levels leads to better patient management, reducing risks of toxicity.

Implication

Reveals a new assay for monitoring mycophenolic acid in plasma, suggesting improved management strategies.

Abstract

Mycophenolic acid (MPA), an immunosuppressive metabolite of Penicillium fungi with a narrow therapeutic window, poses significant clinicals risks of toxicity or transplant rejection if its concentration is not strictly controlled....

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Liu et al. (2026) studied this question.

synapsesocial.com/papers/6a1fc44edee9eb8c0dce5dc9 https://doi.org/10.1039/d6an00484a

View at Publisher

Ask AI

Bookmark

Share

Colloidal gold immunochromatographic assay for mycophenolic acid in human plasma

Key Points

Implication

Abstract

Discussion

Cite This Study

Colloidal gold immunochromatographic assay for mycophenolic acid in human plasma

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

More related papers

More from The Analyst

Keep reading

More related papers

More from The Analyst