Why the study?
Does genetically instrumented higher BMI increase the odds of SARS-CoV-2 infection and COVID-19 severity?
Observational (n=3,181,275)
Yes
Does genetically instrumented higher BMI increase the odds of SARS-CoV-2 infection and COVID-19 severity?
Odds Ratio: 1.57 (95% CI 1.39–1.78)
Genetically higher BMI is causally associated with increased susceptibility to detected SARS-CoV-2 infection and severe COVID-19 disease, and these findings are robust to selection and misclassification biases.
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Allan Mc I. Mowat (1998) conducted an observational in COVID-19 (n=3,181,275). Genetically instrumented BMI vs. Lower BMI was evaluated on SARS-CoV-2 infection and COVID-19 severity (OR 1.57, 95% CI 1.39-1.78).
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