Why the study?
Short-term blood pressure variability is a potential indicator of cardiovascular risk, but its association with arterial stiffness in individuals with prehypertension remains unclear.
Does short-term blood pressure variability associate with arterial stiffness in a prehypertensive population?
Population
8,504 residents aged 35-80 years with office BP 120-139/80-89 mm Hg
Comparison
Short-term systolic BP variability indices derived from 24-hour ABPM
Design
Community-based prospective cohort study
Key result
Short-term daytime systolic blood pressure variability was independently associated with arterial stiffness in prehypertension (OR per unit increase in SD 1.02; 95% CI 1.01-1.04; P<0.05).
Authors
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Does not yet support routine BP variability monitoring in prehypertension; extends observational links to arterial stiffness.
Cohort (n=8,504)
Does short-term blood pressure variability associate with arterial stiffness in a prehypertensive population?
Odds Ratio: 1.02 (95% CI 1.01–1.04)
p-value: p=<0.05
Short-term daytime systolic blood pressure variability is independently associated with arterial stiffness in prehypertensive individuals, suggesting its potential utility for early vascular risk stratification.
Liu et al. (2026) conducted a cohort in Prehypertension (n=8,504). Short-term daytime systolic blood pressure variability was evaluated on Arterial stiffness (baPWV ≥ 1800 cm/s) (OR 1.02, 95% CI 1.01-1.04, p=<0.05). Short-term daytime systolic blood pressure variability was independently associated with arterial stiffness in prehypertension (OR per unit increase in SD 1.02; 95% CI 1.01-1.04; P<0.05).