Association Between Long-Term Blood Pressure Variability and 10-Year Progression in Arterial Stiffness

1122 individuals from the Multiethnic Study of Atherosclerosis, mean age 57 years, 46% males at baseline, who were not taking antihypertensive medications.

Higher long-term systolic blood pressure (SBP) variability (fifth quintile of standard deviation, variability independent of the mean, and coefficient of variation across 5 visits)

Lower long-term SBP variability (first quintile of standard deviation, variability independent of the mean, and coefficient of variation)

10-year percent change in arterial stiffness (measured using carotid distensibility coefficient and Young's elastic modulus at baseline and after a mean of 9.5 years of follow-up)surrogate