Key result
Hypertensive heart disease prevalence rises among working-age adults, driving higher disability in less developed regions.
Why the study?
To characterize global trends, socioeconomic inequalities, and future burden of hypertensive heart disease among working-age adults, focusing on the shift from fatal outcomes to chronic disability.
Observational
Yes
Hypertensive heart disease is an increasing cause of chronic disability among working-age adults globally, particularly in less developed regions.
Answers are grounded in this paper and cite their sources.
Rising prevalence signals growing working-age disability risk from hypertensive heart disease; leaves open causal drivers and targeted prevention in low-resource settings.
Objective: To characterize global trends, socioeconomic inequalities, and future burden of hypertensive heart disease (HHD) among working-age adults, with a focus on the emerging shift from fatal outcomes to chronic disability.Design and method: A population-based observational study was conducted using estimates from a large global disease burden database covering 204 countries and territories from 1990 to 2021. Adults aged 20–64 years were included. Age-standardized prevalence, mortality, and disability-adjusted life year rates were calculated and analysed by age group and sex. Temporal trends were assessed over the study period. The association between socioeconomic development level and disability burden was evaluated at regional and national levels. Results: In 2021, hypertensive heart disease accounted for a substantial burden among working-age adults worldwide. Over the study period, age-standardized prevalence increased, whereas mortality and disability-adjusted life year rates declined. Burden increased markedly with age and was consistently higher in males than in females, with the greatest burden observed among adults aged 45 years and older. A strong inverse association was observed between socioeconomic development level and disability-adjusted life year rates, indicating substantially higher disability burden in less developed regions. Conclusions: Hypertensive heart disease is emerging as a major chronic condition among the global workforce. Rising prevalence combined with persistent socioeconomic inequalities is expected to sustain a substantial health and productivity burden through 2050, highlighting the need for equitable hypertension prevention and long-term management.
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Dong et al. (2026) conducted an observational in Hypertensive heart disease. Socioeconomic development level was evaluated on Age-standardized prevalence, mortality, and disability-adjusted life year rates. From 1990 to 2021, the global age-standardized prevalence of hypertensive heart disease increased among working-age adults, with higher disability burden in less developed regions.
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