Key result
Hypohydration fails to alter perceived exertion or leg pain during BFR exercise.
Why the study?
Blood flow restriction increases perceived effort and pain, and whether hypohydration interacts with blood flow restriction to affect perceptual responses was unknown.
Does hypohydration affect the perceptual response (RPE and leg pain) during blood flow restriction exercise?
Does hypohydration affect the perceptual response (RPE and leg pain) during blood flow restriction exercise?
Hydration status has little impact on perceptual responses such as perceived exertion and leg pain during blood flow restriction exercise.
Hydration control may be unnecessary for perceptual measures in BFR exercise studies; leaves open confirmation in larger trials.
Blood flow restriction (BFR) training has emerged as a novel modality with clinical potential. However, BFR increases perceived effort and pain, highlighting the need to identify factors influencing perceptual responses to optimize its practical application. Hypohydration similarly increases discomfort during exercise or painful stimuli, but whether this interacts with BFR is unknown. The purpose of the study was to determine if hydration affects the perceptual response to BFR exercise. Of the 34 participants recruited, 17 (7 females) completed two BFR exercise bouts: (1) Hydrated (regular fluid intake) and (2) Hypohydrated (24 h fluid restriction). Rating of perceived exertion (RPE) and leg pain were recorded throughout. With hypohydration, urine specific gravity increased (Hydrated = 1.01 ± 0.009, vs. Hypohydrated = 1.025 ± 0.002, p < 0.0001), body mass decreased (-2.3 ± 0.7%, p < 0.0001), and plasma volume decreased (-7.0 ± 3.4%, p < 0.0001). Similar RPE and leg pain were reported during BFR exercise (RPE: 10.6 ± 0.9, vs. 11.1 ± 0.9, p = 0.054, leg pain: 3.5 ± 1.1, vs. 3.8 ± 1.2, p = 0.2). Similarly, during the rest periods, there was a minimal effect for RPE (9.1 ± 1, vs. 9.5 ± 1.3, p = 0.1) and leg pain (3.1 ± 1.5, vs. 3.6 ± 1.8, p = 0.09). Preliminary analyses show minimal sex differences in perceptual responses, with hydration status changes unrelated to BFR perception. Thus, hydration status has little impact on perceptual responses to BFR exercise.
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McCrone et al. (2025) studied this question. Hypohydration vs. Hydrated (regular fluid intake) was evaluated on Rating of perceived exertion (RPE) during BFR exercise (p=0.054). Hypohydration via 24-hour fluid restriction did not significantly alter rating of perceived exertion (11.1 vs 10.6, p=0.054) or leg pain (3.8 vs 3.5, p=0.2) during blood flow restriction exercise.
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