Key result
Antihypertensive treatment linked to ~24% fewer symptoms versus no treatment during home BP monitoring.
Why the study?
To evaluate the frequency of self-reported symptoms under real-life conditions by patients performing home blood pressure monitoring using the Hy-Result web application.
Observational (n=20,900)
Yes
In a real-world analysis of a home blood pressure monitoring app, 20% of reports included self-reported symptoms, with treated patients reporting significantly fewer symptoms than untreated patients.
Treated patients reported fewer symptoms on home BP monitoring; hypothesis-generating association that leaves open causality and should not change practice.
Objective: To evaluate the frequency of self-reported symptoms under real-life conditions by patients performing home blood pressure monitoring (HBPM) using the Hy-Result web application (app). Design and method: Hy-Result® is a validated app endorsed by the French Society of Hypertension (SFHTA) an Belgium Hypertension Committee (BHC), which: i) helps patients measuring BP according to a standardized protocol; ii) automatically interprets the readings; iii) allows measurements to be shared via a PDF report. Each report is generated by a patient measuring BP (morning and evening, 3 measurements per session) for 3 to 7 consecutive days. Data were collected between September 2024 and February 2025. The analyses are based on whether or not antihypertensive medication is taken, self-reported symptoms (headaches, dizziness, pain, etc.) classified into three categories: i) no symptoms, ii) mild symptoms, and iii) severe symptoms, BP levels, and frequency of app use. Results: A total of 20,900 reports were analyzed. Population: average age 65 years; 67% (n=14,052) receiving antihypertensive treatment; 24% (n=5,861) with comorbidities (diabetes, chronic kidney disease, stroke); 58% (n=12,190) male. Among treated patients, 66% (n=92,227) of reports showed BP >130/80; among untreated patients, 43% (n=2,977) of reports confirmed hypertension diagnosis (BP >135/85). Overall, 20% (n=4,175) of reports indicated the presence of symptoms (moderate 17% (n=247), severe 3% (n=607). Significant correlations were observed between symptom frequency and several variables: Younger patients were more symptomatic (p < 0.001). Women reported a higher frequency of symptoms than men (p < 0.001). Patients undergoing treatment were less symptomatic (17.7%, n=2545 vs. 23.4%, n=1630, p < 0.001). Persistant users (3 times or more) reported fewer symptoms compared to first-time users: 25.7% (n=2074) versus 15.3% (n=1444) (p = 0.003). Smoking and alcohol consumption) were significantly correlated with a higher frequency of symptoms (p < 0.001). Higher BP levels (>160/110 mmHg) were associated with more frequent symptoms (p < 0.001). Conclusions: Observing that 20% of patients performing HBPM in real life declare symptoms, and that patients undergoing treatment are less symptomatic (p < 0.001) in the large Hy-Result cohort, presents original data for which there are few comparisons in the literature.
No takes yet. Share an insight, caveat, or question.
Postel‐Vinay et al. (2026) conducted an observational in Hypertension (n=20,900). Antihypertensive treatment vs. No antihypertensive treatment was evaluated on Self-reported symptoms (p=< 0.001). Among patients performing home blood pressure monitoring, those receiving antihypertensive treatment reported significantly fewer symptoms than untreated patients (17.7% vs 23.4%; p<0.001).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: