Key result
Post-TAVR new-onset atrial fibrillation occurred in 9.0% of patients and was associated with older age, higher heart rate, enlarged cardiac chambers, elevated NT-proBNP, and renal dysfunction.
Why the study?
To compare conventional preoperative parameters in TAVR patients with and without post-procedural new-onset atrial fibrillation to identify simple risk markers.
What conventional preoperative parameters are associated with new-onset atrial fibrillation after TAVR?
Observational (n=211)
No
What conventional preoperative parameters are associated with new-onset atrial fibrillation after TAVR?
Conventional preoperative markers, including older age, enlarged cardiac chambers, reduced LVEF, and elevated NT-proBNP, can help identify patients at high risk for new-onset atrial fibrillation after TAVR.
Answers are grounded in this paper and cite their sources.
May support preoperative NOAF risk stratification in TAVR; leaves open need for prospective validation before practice change.
This study compared conventional preoperative parameters between transcatheter aortic valve replacement (TAVR) patients with and without post-procedural new-onset atrial fibrillation (NOAF) to identify simple risk markers. A total of 211 patients undergoing TAVR were enrolled. Post-procedural NOAF occurred in 19 patients (9.0%). Preoperative clinical baseline data, electrocardiographic parameters, conventional echocardiographic indices, laboratory findings, and perioperative variables were compared between the NOAF and No-NOAF groups. Compared with the No-NOAF group, patients with post-TAVR NOAF were significantly older (P = 0.002) and had a higher heart rate (P = 0.002). Echocardiographically, the NOAF group exhibited larger cardiac dimensions, including right ventricular diameter (P < 0.001), pulmonary artery diameter (P = 0.003), right atrial transverse diameter (P < 0.001), left atrial diameter (P = 0.042), and left ventricular diameter (P = 0.018). Moreover, the NOAF group had lower left ventricular ejection fraction (P = 0.005) and fractional shortening (P = 0.006). Laboratory findings showed significantly higher levels of indirect bilirubin, serum creatinine, uric acid, monocyte percentage, and N-terminal pro-brain natriuretic peptide (NT-proBNP) (P < 0.001), as well as lower glomerular filtration rate and total cholesterol (P = 0.009) in the NOAF group. No significant differences were observed in procedure length, valve type, or intraoperative complications (P > 0.05). Older age, higher heart rate, enlarged cardiac chambers (including right heart and left atrium), reduced left ventricular systolic function, elevated NT-proBNP, renal dysfunction, higher uric acid, lower total cholesterol, and increased monocyte percentage are associated with post-TAVR NOAF. These easily accessible conventional markers may facilitate early identification of high-risk patients in routine clinical practice, offering a practical alternative to advanced imaging techniques.
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Tang et al. (2026) conducted an observational in Severe aortic stenosis (n=211). Preoperative clinical, echocardiographic, and laboratory risk markers vs. Patients without these risk markers was evaluated on New-onset atrial fibrillation (NOAF) after TAVR. Post-TAVR new-onset atrial fibrillation occurred in 9.0% of patients and was associated with older age, higher heart rate, enlarged cardiac chambers, elevated NT-proBNP, and renal dysfunction.
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