Key result
New-onset atrial fibrillation occurred in up to 29.04% of patients following transcatheter aortic valve implantation and was associated with increased mortality and thromboembolic events.
Why the study?
New-onset atrial fibrillation after TAVI is linked to increased mortality and complications, motivating an evaluation of its incidence and risk factors associated with mortality and thromboembolic events.
What is the incidence of new-onset atrial fibrillation after TAVI, and does it increase the risk of mortality and thromboembolic complications in adult patients?
Systematic Review
What is the incidence of new-onset atrial fibrillation after TAVI, and does it increase the risk of mortality and thromboembolic complications in adult patients?
New-onset atrial fibrillation is a highly frequent complication after TAVI (affecting up to 29% of patients) and is strongly associated with an increased risk of stroke, all-cause mortality, and hospital readmission, underscoring the need for protocolized post-procedure monitoring and optimal antithrombotic management.
Transcatheter Aortic Valve Implantation (TAVI) is an effective treatment for severe aortic stenosis in high-risk patients; however, atrial fibrillation (AF) is a common complication associated with the procedure. New-Onset Atrial Fibrillation (NOAF) after TAVI is linked to increased mortality and additional complications. This study aimed to evaluate the incidence of NOAF following TAVI and identify risk factors associated with mortality and the development of thromboembolic events. A systematic review of 18 studies was conducted using databases such as MEDLINE/PubMed, EMBASE, Web of Science, Scopus, Cochrane Library, Google Scholar, Wiley Online Library, SciELO, and Redalyc. No language restrictions were applied, and the search covered studies from 2009 to 2024. The follow-up period ranged from 48 h to 730 days, with a mean of 180 days. Early monitoring and management of AF are essential in patients undergoing TAVI. The incidence of NOAF ranged up to 29.04%, meaning about 29 out of every 100 patients were affected. AF rates varied between 7.2% and 37%, with an average of around 20. Standardizing anticoagulation strategies is important to reduce complications. Randomized studies are needed to evaluate the relationship between AF and post-TAVI mortality and to determine whether AF is a marker of higher risk or an independent factor in these patients.
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Montenegro-Palacios et al. (2025) conducted a systematic review in Severe aortic stenosis undergoing TAVI. Transcatheter Aortic Valve Implantation (TAVI) was evaluated on Incidence of New-Onset Atrial Fibrillation (NOAF). New-onset atrial fibrillation occurred in up to 29.04% of patients following transcatheter aortic valve implantation and was associated with increased mortality and thromboembolic events.
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