Mitochondria-Targeted Near-Infrared Fluorescent Carbon Dots for Assessing ATP Levels in Cardiomyocytes under Exercise-Simulated Metabolic Stress

Key Points

• The aim is to assess ATP levels in cardiomyocytes under exercise-induced metabolic stress using a specific nanoprobe.
• Developed a mitochondria-targeted near-infrared fluorescent carbon dot nanoprobe (Mit-CDs) for in situ imaging.
• Conducted experiments to visualize ATP levels in cardiomyocytes.
• Analyzed the response under simulated exercise conditions.
• Demonstrated successful imaging of ATP levels in cardiomyocytes during exercise stress.
• Mit-CDs effectively targeted mitochondria, providing clear ATP visualization.
• Enhancements in understanding cardiac performance under metabolic stress were noted.