Catheter Ablation of Paroxysmal Atrial Fibrillation: Have We Achieved Cure with Pulmonary Vein Isolation?
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Key result
Pulmonary vein isolation is the cornerstone of catheter-based therapies for atrial fibrillation, with wide antral isolation confirmed by circular mapping recommended to optimize clinical success.
Population
Patients with paroxysmal atrial fibrillation (recurrent drug-refractory AF)
Design
Review
Authors
Discussion
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Implication
Confirms wide antral PVI as standard for AF ablation success; leaves open optimal non-PV trigger strategies in recurrences.
Structured PICO
P
Population
Patients with paroxysmal atrial fibrillation (recurrent drug-refractory AF)
I
Intervention
Pulmonary vein isolation (PVI) and additional non-PV ablation
PVI remains the cornerstone of paroxysmal AF ablation, but addressing specific non-PV triggers is necessary in a subset of patients with recurrent arrhythmias.
Limitations
- Available ablation tools for pulmonary vein isolation are still imperfect.
- Pulmonary vein reconnection following isolation represents the dominant mechanism of recurrent arrhythmia.
Cite This Study
Santangeli et al. (2015) conducted a review in Paroxysmal Atrial Fibrillation. Pulmonary vein isolation was evaluated. Pulmonary vein isolation is the cornerstone of catheter-based therapies for atrial fibrillation, with wide antral isolation confirmed by circular mapping recommended to optimize clinical success.
Topics
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