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The vast parallelism, exceptional energy efficiency and extraordinary information density inherent in DNA molecules are being explored for computing, data storage and cryptography. DNA cryptography is a new field of cryptography arising with the research of DNA computing in recent years. In this paper, an encryption scheme is designed by using the technologies of DNA synthesis, PCR amplification and DNA digital coding as well as the theory of traditional cryptography. By applying the special function of primers to PCR amplification, the primers and coding mode are used as the key of the scheme. The traditional encryption method and DNA digital coding are used to preprocess to the plaintext, which can effectively prevent attack from a possible word as PCR primers. Biological difficult issues and cryptography computing difficulties provide a double security safeguards for the scheme. And the security analysis shows that the encryption scheme has high confidential strength. To demonstrate the performance, we present an interesting example to encode and decode message just between specific two persons using the proposed scheme.
Cui et al. (Mon,) studied this question.