Key result
Surgical mitral valve repair remains the gold standard treatment for severe degenerative mitral regurgitation, with early restorative surgery emerging as an important concept for asymptomatic patients.
This review reinforces surgical mitral valve repair as the gold standard for severe degenerative mitral regurgitation and highlights the shift toward early restorative surgery in asymptomatic patients.
Chronic degenerative mitral regurgitation is the most common valvular disease in the United States. The objective of this review article is to impart a balanced understanding of the basic concepts and new developments in assessment and management of patients with severe degenerative mitral regurgitation. Etiologic, epidemiologic, pathologic, and physiopathologic concepts are discussed, as well as the importance of surgical mitral valve repair as the current gold standard treatment. Research efforts in "decoding" the natural history and prognosis of patients with severe degenerative mitral regurgitation have produced important insights into the surgical timing of patients with asymptomatic mitral regurgitation, and the concept of early restorative surgery has emerged.
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Michelena et al. (2011) conducted a review in Severe degenerative mitral regurgitation. Surgical mitral valve repair was evaluated. Surgical mitral valve repair remains the gold standard treatment for severe degenerative mitral regurgitation, with early restorative surgery emerging as an important concept for asymptomatic patients.
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