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Objectives: Evaluating the effect of botox injections on the satisfactory penetrating in women with vaginismus. Methods: A comprehensive systematic search in the electronic databases carried out up to September 2018. All studies that used botox to treat vaginismus were included in this review. Results: Nine cohort studies were included in meta-analysis. Our results indicate that botox can be an option for effective treatment of patients with vaginismus (event rate = 0.855, 95% confidence interval = 0.764 to 0.915; p-value < 0.001). Conclusion: Botox injection can improve vaginismus. However, because of the lack of randomized clinical trials, this conclusion should be carefully interpreted.
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Velayati et al. (2019) studied this question.
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