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October 11, 1997BMJOpen Access

Intraoperative intravascular volume optimisation and length of hospital stay after repair of proximal femoral fracture: randomised controlled trial

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Key result

Intraoperative intravascular volume optimization guided by esophageal Doppler monitoring significantly reduced median hospital stay (12 vs 20 days; P<0.05) after proximal femoral fracture repair.

Why the study?

Does intraoperative intravascular volume optimisation guided by oesophageal Doppler ultrasonography reduce hospital stay in patients undergoing repair of proximal femoral fracture?

Population

40 patients undergoing repair of proximal femoral fracture under general anaesthesia

Comparison

Additional repeated colloid fluid challenges… vs Conventional intraoperative fluid management

Design

RCT, Randomly assigned

Follow-up

Until hospital discharge

Authors

SSS. SinclairUniversity College LondonSJS. JamesSunnybrook Health Science CentreMSMervyn SingerBury College

Discussion

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Implication

Supports esophageal Doppler-guided volume optimization in hip fracture repair; extends goal-directed fluid therapy evidence to orthopedic trauma.

Study Design

Type

RCT (n=40)

Randomization

randomly assigned

Multicenter

No

Structured PICO

Does intraoperative intravascular volume optimisation guided by oesophageal Doppler ultrasonography reduce hospital stay in patients undergoing repair of proximal femoral fracture?

P
Population
40 patients undergoing repair of proximal femoral fracture under general anaesthesia.
I
Intervention
Additional repeated colloid fluid challenges with oesophageal Doppler ultrasonography used to maintain maximal stroke volume throughout the operative period
C
Comparator
Conventional intraoperative fluid management
O
Outcome
Time declared medically fit for hospital discharge, duration of hospital stay (in acute bed; in acute plus long stay bed), mortality, and perioperative haemodynamic changes

Main Result

Effect estimate: 39% reduction

Absolute Event Rate: 12% vs 20%

p-value: p=<0.05

Intraoperative intravascular volume optimization guided by esophageal Doppler monitoring significantly reduces hospital stay in patients undergoing hip fracture repair.

Cite This Study

Sinclair et al. (1997) conducted an RCT in proximal femoral fracture (n=40). Intraoperative intravascular volume optimisation with repeated colloid fluid challenges monitored by oesophageal Doppler ultrasonography vs. Conventional intraoperative fluid management was evaluated on Duration of hospital stay (39% reduction, p=<0.05). Intraoperative intravascular volume optimization guided by esophageal Doppler monitoring significantly reduced median hospital stay (12 vs 20 days; P<0.05) after proximal femoral fracture repair.

synapsesocial.com/papers/6a1fdb49ea3607bd19ae8978https://doi.org/10.1136/bmj.315.7113.909
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1The Role of Physiologic Monitoring in Patients with Fractures of the Hip1985 · 148 citations
  2. 2Effects of alterations in left ventricular filling, contractility, and systemic vascular resistance on the ascending aortic blood velocity waveform of normal subjects1991 · 143 citations
  3. 3Prediction of Rehabilitation after Hip Fracture1995 · 139 citations
  4. 4Differences in mortality after fracture of hip: the East Anglian audit1995 · 326 citations
  5. 5Mortality and morbidity after hip fractures.1993 · 882 citations