Why the study?
Does (pro)renin receptor blocker (PRRB) reduce retinal inflammation in animal models of streptozotocin-induced diabetes?
Population
Long-Evans rats, C57BL/6 mice, and angiotensin II type 1 receptor-deficient mice with streptozotocin-induced…
Design
Preclinical
Authors
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Supports (pro)renin receptor blockade in diabetic retinopathy models; hypothesis-generating pending human trials.
Does (pro)renin receptor blocker (PRRB) reduce retinal inflammation in animal models of streptozotocin-induced diabetes?
Blockade of the (pro)renin receptor reduces retinal inflammation in diabetic animal models, highlighting a potential novel target for diabetic retinopathy.
Satofuka et al. (2009) studied this question.
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