Key result
Actin was identified as a key component in cellular motility during the late 1960s through independent research involving biochemistry, microscopy, and inhibitory natural products.
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Design
Retrospective review
Historical review of actin discovery reinforces interdisciplinary methods; leaves open translation to cardiovascular cell research.
During the late 1960s four independent lines of research implicated actin in cellular motility. This Retrospective recounts how biochemistry, light and electron microscopy, and inhibitory natural products all contributed to this breakthrough.
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Thomas D. Pollard (2022) studied this question. Actin was identified as a key component in cellular motility during the late 1960s through independent research involving biochemistry, microscopy, and inhibitory natural products.
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