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March 24, 1997The Journal of Cell BiologyOpen Access

Accelerating on a Treadmill: ADF/Cofilin Promotes Rapid Actin Filament Turnover in the Dynamic Cytoskeleton

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JTJulie A. TheriotHoward Hughes Medical Institute

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Implication

Challenges translation of in vitro ADF/cofilin data to cells; leaves open mechanisms reconciling in vivo actin discrepancies.

Key Points

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Cite This Study

Julie A. Theriot (1997) studied this question.

synapsesocial.com/papers/6a7d97d3c108c8d3ff044fc0 https://doi.org/10.1083/jcb.136.6.1165

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Recent quantitative studies of actin filament turnover during cell locomotion1993 · 118 citations
2Cofilin is an essential component of the yeast cortical cytoskeleton.1993 · 253 citations
3Human actin depolymerizing factor mediates a pH-sensitive destruction of actin filaments1993 · 281 citations
4Xenopus Actin Depolymerizing Factor/Cofilin (XAC) Is Responsible for the Turnover of Actin Filaments in Listeria monocytogenes Tails1997 · 218 citations
5Actin filaments and the growth, movement, and spread of the intracellular bacterial parasite, Listeria monocytogenes.1989 · 1,281 citations