Why the study?
Do ANP and BNP levels accurately diagnose impaired left ventricular diastolic function in patients with nonvalvular persistent atrial fibrillation?
Do ANP and BNP levels accurately diagnose impaired left ventricular diastolic function in patients with nonvalvular persistent atrial fibrillation?
Natriuretic peptides, particularly BNP, are highly sensitive and specific markers for diagnosing underlying left ventricular diastolic dysfunction in patients with persistent atrial fibrillation.
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BNP thresholds during AF may identify diastolic dysfunction; hypothesis-generating and requires prospective validation before clinical adoption.
Bąkowski et al. (2009) studied this question.
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