Key result
In a cohort of 1,109 Japanese patients undergoing elective isolated off-pump coronary artery bypass grafting, the early postoperative mortality rate was 0.5%, demonstrating satisfactory outcomes in this population.
Observational (n=1,109)
No
In a high-volume Japanese center, off-pump coronary artery bypass grafting demonstrated a low early postoperative mortality rate of 0.5%, with reduced preoperative LVEF identified as a significant risk factor for early death.
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Supports off-pump CABG feasibility with low mortality in high-volume Japanese centers; leaves open broader generalizability and randomized confirmation.
Background: Off-pump coronary artery bypass grafting (OPCAB) has evolved into a standard technique in coronary artery bypass grafting. However, a detailed investigation in Japanese population undergoing OPCAB has not yet been fully elucidated.Methods: A total of 1109 consecutive patients undergoing isolated OPCAB between 2006 and 2013 at Juntendo University were reviewed. The data was evaluated in the light of previously published OPCAB-associated reports.Results: There were 904 male (81.5%) and a mean was 67.5 ± 9.8 years. Eight patients (0.5%) died within 30 days postoperatively or before discharge, which was equivalent to or rather better than the previously reported mortality rates, including the European System for Cardiac Operation Risk Evaluation II (2.1 ± 2.1) data. A morbidity analysis revealed that prolonged intubation (>24 h) occurred in 43 patients (3.6%), surgical site infections in 18 (1.9%), neurological complications in 13 (1.3%). A reduced preoperative left ventricular ejection fraction (less than 40%) was found to be a risk factor for early postoperative death (odds ratio 10.58, respectively, p <0.05) in our cohort.Conclusions: Early postoperative mortality and morbidity rates in Japanese population after OPCAB were rather satisfactory and similar to those reported by other countries.
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Kuroda et al. (2015) conducted an observational in Coronary artery disease requiring bypass grafting (n=1,109). Off-pump coronary artery bypass grafting (OPCAB) was evaluated on Early postoperative mortality (within 30 days or before discharge). In a cohort of 1,109 Japanese patients undergoing elective isolated off-pump coronary artery bypass grafting, the early postoperative mortality rate was 0.5%, demonstrating satisfactory outcomes in this population.
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