Systemic chemotherapy followed by radiotherapy achieved complete remission for 30 months without recurrence or arrhythmias in a patient with primary cardiac lymphoma.
Case Report (n=1)
No
Does systemic chemotherapy followed by radiotherapy improve survival and achieve remission in a patient with primary cardiac B cell lymphoma presenting with ventricular tachycardia?
Rapid diagnosis and treatment with chemotherapy followed by radiotherapy can achieve long-term survival and complete remission in primary cardiac lymphoma presenting with ventricular tachycardia.
We experienced a long-term survival case of primary cardiac lymphoma (PCL) demonstrating ventricular tachycardia (VT) as an initial sign, which was related to localized myocardial damage by lymphoma cells. A 70-year-old woman with sustained VT was admitted to the Kofu Municipal Hospital. VT ceased with the administration of disopyramide intravenously. The origin of the VT was the free wall of the right ventricular outflow tract (RVOT) as observed by electrocardiography on admission. A solitary mass in the free wall of the RVOT was found by echocardiography, chest computed tomographic scanning and magnetic resonance imaging. There was no evidence of extracardiac involvement. The patient was histologically diagnosed as PCL by endomyocardial biopsy. Chemotherapy started immediately after the diagnosis and the mass showed a marked reduction in size. After 8 cycles of chemotherapy, radiotherapy was performed. Pericardial thickness in the free wall of the RVOT developed without severe side effects. Complete remission has been maintained for 30 months after the initial diagnosis, and no recurrence and arrhythmias have been detected during the follow-up period. It was demonstrated that rapid diagnosis and chemotherapy followed by radiotherapy for PCL achieved better survival.
Miyashita et al. (Sat,) conducted a case report in Primary cardiac lymphoma with ventricular tachycardia (n=1). Systemic chemotherapy and radiotherapy was evaluated on Complete remission and survival. Systemic chemotherapy followed by radiotherapy achieved complete remission for 30 months without recurrence or arrhythmias in a patient with primary cardiac lymphoma.