What question did this study set out to answer?

The study aims to explore histological findings in cases of Adams-Stokes syndrome with heart-block.

June 1, 1914Archives of Internal Medicine

Three Cases of Adams-Stokes Syndrome With Histological Findings

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Population

3 patients with a clinical history suggesting heart-block. Case 1 is detailed as a 75-year-old male with…

Design

Case_series

Authors

AOAdéle OppenheimerMount Sinai Hospital

Discussion

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Implication

Raises awareness for conduction lesions in Adams-Stokes; leaves open systematic histological correlation in contemporary cohorts.

Key Points

The study aims to explore histological findings in cases of Adams-Stokes syndrome with heart-block.
Microscopic examination of three heart specimens with clinical histories suggesting heart-block.
Post-mortem assessments conducted by experienced pathologists.
Histological analysis focused on lesions within the conducting system.
Identified three distinct histological conditions related to heart-block.
Case one revealed a calcareous nodule in the bundle of His, correlating with complete heart-block.
Clinical data were insufficient to fully explain the observed conduction failures.

Structured PICO

Population

3 patients with a clinical history suggesting heart-block (Adams-Stokes syndrome). Case 1 is detailed as a 75-year-old male with slow pulse, vertiginous and syncopal attacks, and rapid venous pulse.

Intervention

Post-mortem histological examination of the cardiac conducting system

Outcome

Histological conditions in the conducting systemsurrogate

This early case series demonstrates that Adams-Stokes syndrome can be associated with diverse histological lesions in the cardiac conducting system, such as calcification of the bundle of His.

Limitations

Clinical data do not give definite information of the mechanism of the heart that can be positively correlated with post-mortem findings

Cite This Study

Adéle Oppenheimer (1914) studied this question.

synapsesocial.com/papers/6a1febdf8fbc0747110da369 https://doi.org/10.1001/archinte.1914.00070120119010

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Three Cases of Adams-Stokes Syndrome With Histological Findings

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Three Cases of Adams-Stokes Syndrome With Histological Findings

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

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