Why the study?
Does type II diabetes mellitus worsen the angiographic severity of coronary artery disease in Arab women?
Does type II diabetes mellitus worsen the angiographic severity of coronary artery disease in Arab women?
Arab women with type II diabetes exhibit more severe, diffuse, and distal coronary artery disease on angiography compared to non-diabetics, although distal vessels remain similarly suitable for grafting.
May signal more complex CAD patterns in diabetic Arab women; leaves open causality and requires prospective validation before practice implications.
OBJECTIVE: To compare angiographic features in women with and without type II diabetes mellitus. SUBJECTS AND METHODS: One hundred and six consecutive women who underwent diagnostic coronary angiography in the Chest Diseases Hospital, Kuwait, were chosen for the study. Quantitative coronary angiography was performed and the angiographic features were assessed. RESULTS: Eighty-two patients had coronary artery disease. Of these, 59 (72%) had type II diabetes mellitus and 23 (28%) were non-diabetics. Segmental disease involving the mid and distal left anterior descending artery was more common in diabetics than non-diabetics. Diabetics had a greater number of long lesions and more distal coronary artery disease. However, the caliber and suitability of the distal vessels for grafting was similar. CONCLUSION: Angiographic severity of coronary artery disease in this selective group of mostly Arab women was more in those with type II diabetes mellitus than non-diabetics. However, the distal luminal diameter was similar in both groups.
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Thomas et al. (2002) studied this question.
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