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February 1, 1993Diabetes Care

Diabetes, Other Risk Factors, and 12-Yr Cardiovascular Mortality for Men Screened in the Multiple Risk Factor Intervention Trial

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Authors

Jeremiah Stamler
Jeremiah StamlerPreventive Cardiology
OVOlga VaccaroFederico II University HospitalJNJames D. NeatonPreventive Cardiology

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Overview

Long-term cohort study demonstrates elevated cardiovascular mortality in diabetic men, highlighting the need for aggressive risk factor control.

Key Points

  • To evaluate the impact of diabetes and concurrent cardiovascular risk factors on 12-year cardiovascular mortality.
  • Analyzed 12-year cardiovascular mortality outcomes among men screened for the Multiple Risk Factor Intervention Trial.
  • Assessed the contributions of key modifiable risk factors, including blood pressure, serum cholesterol levels, and cigarette smoking.
  • Sustained intervention targeting blood pressure reduction, cholesterol lowering, and smoking cessation is essential to mitigate high cardiovascular mortality in individuals with diabetes.
  • Population-wide nutritional and hygienic strategies are required to prevent the development of diabetes and associated vascular complications.

Cite This Study

Stamler et al. (1993) studied this question.

synapsesocial.com/papers/69a1cf185eb5690d3d7148edhttps://doi.org/10.2337/diacare.16.2.434
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Mortality from coronary heart disease and stroke in relation to degree of glycaemia: the Whitehall study.1983 · 639 citations
  2. 2Toward a Basic Understanding of Diabetic Complications1991 · 10 citations
  3. 3Insulin and Cardiovascular Disease: Paris Prospective Study1991 · 211 citations
  4. 4Summary of the second report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel II)1993 · 27,987 citations