What question did this study set out to answer?

Determine whether conventional cardiovascular risk factors reliably predict ischaemic heart disease and all-cause mortality in individuals with type 2 diabetes.

June 1, 1991Diabetic Medicine

Are Conventional Risk Factors for Mortality Relevant in Type 2 Diabetes?

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Determine whether conventional cardiovascular risk factors reliably predict ischaemic heart disease and all-cause mortality in individuals with type 2 diabetes.
Followed 191 men with type 2 diabetes mellitus participating in the Whitehall Survey over a 15-year period.
Assessed four conventional risk factors for ischaemic heart disease: plasma cholesterol, systolic blood pressure, cigarette smoking, and body mass index.
Analyzed associations with mortality using univariate Cox regression analysis and reviewed findings across comparable published studies.
Age-adjusted all-cause and ischaemic heart disease mortality rates were significantly increased in men with type 2 diabetes.
Systolic blood pressure was the only conventional risk factor among the four evaluated that significantly predicted mortality in univariate Cox regression analysis.

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Implication

Prospective cohort study uncovers that only systolic blood pressure predicts mortality among conventional risk factors in diabetic men, suggesting standard cardiovascular models may not fit diabetes.

Cite This Study

Fitzgerald et al. (1991) studied this question.

synapsesocial.com/papers/6a0fed09b6f5ee0401601a1d https://doi.org/10.1111/j.1464-5491.1991.tb01635.x

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Implication

Prospective cohort study uncovers that only systolic blood pressure predicts mortality among conventional risk factors in diabetic men, suggesting standard cardiovascular models may not fit diabetes.

Are Conventional Risk Factors for Mortality Relevant in Type 2 Diabetes?

Key Points

Discussion

Implication

Cite This Study

Are Conventional Risk Factors for Mortality Relevant in Type 2 Diabetes?

Key Points

Discussion

Implication

Cite This Study

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