Key result
Hyperglycemia, proteinuria, hypertension, IHD symptoms, age, and smoking predict 10-year cardiovascular mortality in diabetic patients.
Why the study?
Risk factors predicting cardiovascular death in diabetic patients with 1-10 years duration were not fully characterized by treatment type and sex differences.
Population
4591 diabetic out-patients aged 18-67 years with 1-10 years diabetes duration
Comparison
Insulin-treated vs non-insulin-treated patients
Design
Cross-sectional study with multiple logistic regression analysis
Follow-up
10 years
Authors
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Supports CV risk stratification in diabetes; leaves open whether modifying these factors reduces mortality in trials.
Cross-Sectional (n=4,591)
Classic cardiovascular risk factors, including hyperglycemia, proteinuria, and hypertension, are strong predictors of 10-year cardiovascular mortality in diabetic patients, with risk profiles varying by sex and insulin treatment status.
Janeczko et al. (1991) conducted a cross-sectional in Diabetes (n=4,591). Baseline risk factors (hyperglycaemia, proteinuria, arterial hypertension, smoking, age) was evaluated on Total cardiovascular deaths, deaths from ischaemic heart disease, and from stroke. Hyperglycaemia, proteinuria, arterial hypertension, ischaemic heart disease symptoms, age, and smoking were important predictors of cardiovascular mortality in diabetic patients over 10 years.
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