Why the study?
Does single bolus induced hypoglycaemia cause QT prolongation in subjects with type 1 diabetes mellitus?
Does single bolus induced hypoglycaemia cause QT prolongation in subjects with type 1 diabetes mellitus?
This study investigates the physiological effect of rapid, bolus-induced hypoglycemia on the QT interval in patients with type 1 diabetes.
Hypoglycemia QT effects in T1DM remain hypothesis-generating; leaves open arrhythmia prevention strategies in clinical care.
Prolongation of QT interval on the ECG has been shown to be possibly associated with hypoglycaemia. In this study we investigated QT prolongation in episodes of single bolus induced hypoglycaemia in ten subjects with known type 1 diabetes mellitus.
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Christensen et al. (2007) studied this question.
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