Key result
Lercanidipine significantly reduced diastolic blood pressure compared to placebo (-10.3 vs -6.1 mmHg; p<0.05) and yielded a higher responder rate (59.1% vs 37.8%; p<0.05).
Why the study?
Does lercanidipine reduce diastolic blood pressure in elderly patients with mild to moderate hypertension?
RCT (n=144)
Double-blind
Randomized
Yes
Does lercanidipine reduce diastolic blood pressure in elderly patients with mild to moderate hypertension?
Lercanidipine effectively and safely reduces diastolic blood pressure in elderly patients with mild to moderate hypertension without causing reflex tachycardia.
Supports lercanidipine for elderly mild-moderate hypertension; extends RCT evidence to this population.
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Ninci et al. (2011) conducted an RCT in Mild to moderate hypertension (n=144). Lercanidipine vs. Placebo was evaluated on Reduction in diastolic blood pressure (p=<0.05). Lercanidipine significantly reduced diastolic blood pressure compared to placebo (-10.3 vs -6.1 mmHg; p<0.05) and yielded a higher responder rate (59.1% vs 37.8%; p<0.05).
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