Why the study?
Does substrate-enriched warm continuous antegrade blood cardioplegia improve mechanical performance and mechanoenergetic efficiency in pigs on cardiopulmonary bypass?
Population
Pigs on cardiopulmonary bypass (n=21)
Comparison
Warm continuous antegrade blood cardioplegia… vs WCBC alone (n=7)
Design
Preclinical
Follow-up
Twice after 3 hours of WCBC
Authors
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Severely depresses LV function and efficiency despite enrichment in pigs; leaves open optimal cardioplegia strategies for clinical CPB.
Does substrate-enriched warm continuous antegrade blood cardioplegia improve mechanical performance and mechanoenergetic efficiency in pigs on cardiopulmonary bypass?
Prolonged warm continuous antegrade blood cardioplegia severely depresses cardiac contractile function and mechanoenergetic efficiency, even with substrate enrichment.
Korvald et al. (2001) studied this question.
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