Answers are grounded in this paper and cite their sources.
The digestion of chromatin insitu with DNase I reveals, after denaturation, a regular series of single stranded DNA fragments the lengths of which represent multiples of 10 bases. These experiments are compatible with the DNA being on the outside of the chromatin subunit and suggest that the subunit structure itself contains repetitive structural elements. Possible models are discussed.
No takes yet. Share an insight, caveat, or question.
Markus Noll (1974) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: