Key result
Long QT syndrome is an inherited or de novo ion channelopathy causing life-threatening arrhythmias and intrauterine death, with a reported prevalence as high as 1:2000.
Long QT syndrome can present in the fetus and be genetically confirmed.
Fetal LQTS presentation warrants genetic confirmation; extends phenotypic spectrum in case reports but leaves broader implications open.
Long QT syndrome (LQTS) is an ion channelopathy that may cause life-threatening ventricular arrhythmias resulting in intrauterine death, cardiac arrest, or sudden death at any age.1–3 LQTS is often an inherited condition but may present as a de novo mutation, and its prevalence has been reported as high as 1:2000.4
No takes yet. Share an insight, caveat, or question.
Zidere et al. (2022) studied this question. Long QT syndrome is an inherited or de novo ion channelopathy causing life-threatening arrhythmias and intrauterine death, with a reported prevalence as high as 1:2000.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: