Key result
An abnormally high scavenger receptor A index (≥30) was observed in 82.4% of AMI, 75.9% of UA, and 70.3% of SA patients at hospitalization, indicating disrupted, fissured, or eroded plaque.
Why the study?
Is an abnormally high scavenger receptor A (SRA) index a useful indicator of disrupted, fissured, or eroded plaque in patients with acute coronary syndromes?
Population
395 patients, including 225 with acute myocardial infarction, 79 with unstable angina, and 91 with stable…
Design
Cross-sectional
Follow-up
up to 2 days post-hospitalization for a subset
Authors
Loading...
Supports SRA index as potential ACS biomarker; leaves open clinical utility pending prospective validation.
Observational (n=395)
Is an abnormally high scavenger receptor A (SRA) index a useful indicator of disrupted, fissured, or eroded plaque in patients with acute coronary syndromes?
An abnormally high SRA index (≥30) in peripheral blood monocytes may serve as a useful biomarker for disrupted, fissured, or eroded plaques in patients with acute coronary syndromes.
Emura et al. (2007) conducted an observational in Acute coronary syndromes (n=395). Scavenger receptor A (SRA) index was evaluated on SRA index ≥30 at hospitalization. An abnormally high scavenger receptor A index (≥30) was observed in 82.4% of AMI, 75.9% of UA, and 70.3% of SA patients at hospitalization, indicating disrupted, fissured, or eroded plaque.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: