Key result
Severe coronary stenosis linked to ~9-fold higher odds of duty-related cardiac death in firefighters.
Why the study?
Are specific pathoanatomic findings (cardiomegaly, left ventricular hypertrophy, coronary stenosis, prior myocardial infarction) associated with duty-related cardiac death in male US firefighters?
Population
627 male US firefighters aged 18 to 65 years who died on duty between 1999 and 2014.
Design
Case-control
Authors
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May support targeted screening for severe stenosis in male firefighters; leaves open impact on duty-related mortality.
Case-Control (n=627)
Are specific pathoanatomic findings (cardiomegaly, left ventricular hypertrophy, coronary stenosis, prior myocardial infarction) associated with duty-related cardiac death in male US firefighters?
Odds Ratio: 9.3 (95% CI 5.3–16.1)
Absolute Event Rate: 59.8% vs 8.3%
p-value: p=<0.001
Cardiomegaly, severe coronary artery stenosis, and prior myocardial infarction are strongly associated with duty-related sudden cardiac death in US firefighters, highlighting the potential value of targeted screening.
Smith et al. (2018) conducted a case-control in Duty-related cardiac death (n=627). Severe coronary artery stenosis (≥75%) vs. Noncardiac trauma controls was evaluated on Duty-related cardiac death (OR 9.3, 95% CI 5.3-16.1, p=<0.001). Severe coronary artery stenosis (≥75%) was a strong independent predictor of duty-related cardiac death among male firefighters, associated with a 9.3-fold increased odds of cardiac death.
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