Key result
Alfentanil at 20 µg/kg effectively alleviated the hemodynamic responses to both tracheal intubation and suspension laryngoscopy, whereas 10 µg/kg only blocked responses to intubation.
Why the study?
Does alfentanil reduce hemodynamic responses to tracheal intubation and suspension laryngoscopy in patients undergoing laryngoscopic surgery?
RCT (n=75)
Randomly divided
Does alfentanil reduce hemodynamic responses to tracheal intubation and suspension laryngoscopy in patients undergoing laryngoscopic surgery?
p-value: p=<0.05
Alfentanil 20 μg/kg effectively blunts the acute hemodynamic responses to both tracheal intubation and suspension laryngoscopy without significantly delaying recovery.
Favors alfentanil 20 µg/kg for hemodynamic stability in laryngoscopy; extends intubation data to suspension laryngoscopy.
Background: Laryngoscopy, tracheal intubation and suspension laryngoscopy may cause acute hemodynamic responses such as hypertension and tachycardia. Thus, anesthetic technique during laryngoscopic surgery should be focused on sufficient anesthetic depth and rapid recovery. We investigated the effects of alfentanil to hemodynamic responses and recovery during laryngoscopic surgery.
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Kim et al. (2006) conducted an RCT in Laryngoscopic surgery (n=75). Alfentanil vs. Intravenous normal saline was evaluated on Hemodynamic responses (blood pressure and heart rate) to tracheal intubation and suspension laryngoscopy (p=<0.05). Alfentanil at 20 µg/kg effectively alleviated the hemodynamic responses to both tracheal intubation and suspension laryngoscopy, whereas 10 µg/kg only blocked responses to intubation.
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