Key result
Patient activities and morning hours act as triggers for acute myocardial infarction by producing hemodynamic and prothrombotic forces that disrupt vulnerable atherosclerotic plaques.
Design
Review
Authors
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Should not yet change practice; leaves open whether targeting morning triggers improves outcomes in trials.
Insight into the morning triggering of acute myocardial infarction and plaque vulnerability may inform new preventive strategies.
Kondo et al. (1995) conducted a review in Acute myocardial infarction. Physical and physiological stressors (triggers) was evaluated. Patient activities and morning hours act as triggers for acute myocardial infarction by producing hemodynamic and prothrombotic forces that disrupt vulnerable atherosclerotic plaques.
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