Population
Mouse model of pulmonary arterial hypertension (PAH) with a dominant negative BMPRII mutation
Design
Preclinical
Authors
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Facilitates standardized RV assessment in murine PAH models; leaves open clinical translation pending validation.
Provides a detailed echocardiography protocol for assessing right ventricular and pulmonary vascular function in murine models of pulmonary arterial hypertension.
Brittain et al. (2013) studied this question.
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