Key result
The actin-organizing protein Fhod3 is required for postnatal cardiac development and functional maintenance of the adult mouse heart by modulating hypertrophic changes.
Animal study reveals essential roles of Fhod3 in cardiac growth and hypertrophy in mice, indicating its critical requirement for adult heart maintenance.
-deleted mice than in the control mice, suggesting that Fhod3 modulates hypertrophic changes in the adult heart. We conclude that Fhod3 plays a crucial role in both postnatal cardiac development and functional maintenance of the adult heart.
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Ushijima et al. (2017) studied this question. The actin-organizing protein Fhod3 is required for postnatal cardiac development and functional maintenance of the adult mouse heart by modulating hypertrophic changes.
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