Key result
Early 99mTc radionuclide imaging was unilaterally positive in the temporal lobe area in all 8 patients with herpes simplex encephalitis, suggesting its utility in guiding brain biopsy.
Why the study?
Does radionuclide imaging with 99mTc help diagnose herpes simplex encephalitis?
Population
8 patients with herpes simplex encephalitis diagnosed at the University of Kansas Medical Center from 1966…
Design
Case_series
Authors
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Hypothesis-generating for 99mTc-guided biopsy in HSE; does not support practice change without prospective validation.
Observational (n=8)
No
Does radionuclide imaging with 99mTc help diagnose herpes simplex encephalitis?
Radionuclide imaging with 99mTc can suggest herpes simplex as the specific etiology in cases of encephalitis and indicate the best site for brain biopsy.
Karlin et al. (1978) conducted an observational in Herpes simplex encephalitis (n=8). 99mTc radionuclide imaging was evaluated on Unilaterally positive images in the temporal lobe area. Early 99mTc radionuclide imaging was unilaterally positive in the temporal lobe area in all 8 patients with herpes simplex encephalitis, suggesting its utility in guiding brain biopsy.
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